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filingDate 2018-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2020-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111031789-A
titleOfInvention Animal Models and Therapeutic Molecules
abstract The invention particularly relates to a rodent or rodent cell having a genome comprising i) one or more companion animal IGH V region genes, one or more companion animal D region genes and a and (ii) optionally one or more companion animal IGLκV region genes and one or more companion animal IGLκJ region genes; and/or one or more companion animal IGLλV region genes and one or more companion animal IGLλJ region genes, wherein the rodent or rodent cell is capable of expressing the one or more companion animal variable region genes that form the antibody chain, and wherein the species of the companion animal is not rodent.
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