Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44ae178fe5ea1fd193b8e5e1baf1ab3b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 |
filingDate |
2019-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc7abeb691b8f20a31db54943330ba2e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17ae54c896879c9f004d3c6661793a9c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74bed4cd99de8bcce859fbdc57b19a61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5577cb51b8cf5b8dc4f3a2c69f42d14c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6dce906bb9c7871d1afa5ac415d0aa8 |
publicationDate |
2020-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-111020032-A |
titleOfInvention |
Application of miRNA-196b as a molecular marker and therapeutic target for non-small cell lung cancer |
abstract |
The invention discloses the application of miRNA-196b as a molecular marker of non-small cell lung cancer. The present invention finds for the first time that the tumor suppressor gene QKI-5 gene silencing can promote the expression of miRNA-196b in lung cancer cells, and the expression of miR-196b can promote the proliferation, migration and cell cycle progression of non-small cell lung cancer cells by inhibiting its target genes GATA6 and TSPAN12, thereby improving tumor reproduction in animals. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112980957-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112980957-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115993455-A |
priorityDate |
2019-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |