http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111019828-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0861 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-069 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-0647 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-0694 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2513-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-74 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0609 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M23-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M23-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-5027 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-075 |
filingDate | 2019-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111019828-B |
titleOfInvention | Open type high-flux microfluidic oocyte dynamic three-dimensional culture chip and application thereof |
abstract | The invention belongs to the field of life science and engineering, and particularly relates to an open type high-flux microfluidic oocyte dynamic three-dimensional culture chip and application thereof. The chip comprises a micro-flow channel, a cavity used for collecting waste liquid at the tail end of the micro-flow channel and a cylindrical cavity, wherein the cylindrical cavity is arranged on the micro-flow channel, the upper end of the cylindrical cavity is open, and the lower end of the cylindrical cavity is communicated with the micro-flow channel; the microfluidic channel comprises a channel inlet part, a tree-shaped structure diffusion channel and a plurality of rows of microfluidic straight channels connected with the tree-shaped structure diffusion channel, and the cylindrical cavity is arranged on each microfluidic straight channel. The invention provides an open type high-flux micro-fluidic oocyte dynamic three-dimensional culture chip, which utilizes the flow of cell culture solution in a micro-fluidic channel to bring fresh nutrient substances to cells in hydrogel and can also bring away metabolites, and gas can directly permeate the hydrogel through an opening at the upper end of a cylindrical cavity to meet the requirement of cell culture, thereby realizing the three-dimensional dynamic culture of the cells. |
priorityDate | 2019-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.