http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111018771-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-14
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-14
filingDate 2018-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111018771-B
titleOfInvention Method for synthesizing 3- (2-cyanovinyl) indole derivative
abstract The invention discloses a method for synthesizing a 3- (2-cyanovinyl) indole derivative. The reaction takes indole derivatives with low price, easy obtaining and structural diversity as raw materials to carry out continuous Friedel-Crafts reaction/elimination reaction with 3-dimethylamino acrylonitrile in the presence of Lewis acid, so as to synthesize the 3- (2-cyanovinyl) indole derivatives. Compared with the reported synthetic method of the 3- (2-cyanovinyl) indole derivative, the method has the advantages of cheap and easily obtained raw materials, low toxicity, simple and convenient operation, mild synthetic reaction conditions and high efficiency.
priorityDate 2018-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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