http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111012942-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-622 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-04 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L24-0042 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L24-08 |
| filingDate | 2020-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111012942-B |
| titleOfInvention | Hemostatic microsphere for bleeding of artery and vein and viscera and preparation method thereof |
| abstract | The invention discloses a hemostatic microsphere for artery and vein and organ bleeding and a preparation method thereof, wherein the preparation method comprises the following steps: (1) dissolving soluble silk fibroin in an inorganic salt solution to obtain a silk fibroin solution with the mass volume percentage concentration of 1-7% for later use; dissolving sodium alginate in another inorganic salt solution to obtain a sodium alginate solution with the mass volume percentage concentration of 0.5-5% for later use; (2) mixing the silk fibroin solution obtained in the step (1) with a sodium alginate solution to obtain a water phase; adding span 80 and tween 80 into liquid paraffin, heating in water bath, and stirring to obtain oil phase; (3) adding the water phase obtained in the step (2) into the oil phase, uniformly stirring, and then adding a cross-linking agent to react for a period of time to obtain a microsphere solution; (4) and (4) eluting the microsphere solution obtained in the step (3) for multiple times by using a solvent, filtering and drying to obtain the hemostatic microspheres. The hemostatic microsphere has rapid hemostatic effect, good biocompatibility, and degradability in vivo. |
| priorityDate | 2020-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.