http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111001042-B
Outgoing Links
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-602 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-414 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-622 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01D5-0076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D04H1-4382 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D04H1-728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01D5-003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-26 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01D5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D04H1-728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D04H1-4382 |
filingDate | 2019-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111001042-B |
titleOfInvention | Completely degradable tissue engineering skin scaffold material and preparation method thereof |
abstract | The invention discloses a completely degradable tissue engineering skin scaffold material, which comprises a bacterial cellulose/chitosan nano fiber layer and a large-aperture array micrometer fiber scaffold, wherein the bacterial cellulose/chitosan nano fiber layer is an upper layer, a lower layer is arranged above the large-aperture array micrometer fiber scaffold, and the layers are combined by glutaraldehyde through crosslinking; the bacterial cellulose/chitosan nanofiber layer is synthesized in situ by gluconacetobacter xylinus, and cellulase is fixed on the surface of the bacterial cellulose/chitosan nanofiber layer; the large-aperture array micro-fiber scaffold is a scaffold with orderly arranged electrospun lactic acid/hyaluronic acid/fibroin micro-nano fibers, and polylactic acid-glycolic acid growth factor sustained-release microspheres are modified on the surface. The raw materials used in the invention are nontoxic and harmless, the fiber property is stable, the biocompatibility is good, the fiber can be completely degraded in vivo, the pore diameter of the lower layer bracket is close to the cell size, the cell can enter, the growth factor can be stably released, and the regeneration of skin tissues is facilitated. |
priorityDate | 2019-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 114.