abstract |
The invention discloses a method for synthesizing a homoallylic amine compound, belonging to the field of organic synthesis. The invention uses the N, N-acetal compound shown in the formula (I) as a substrate, and the N, N-acetal compound and the nucleophilic reagent allyl silicon compound shown in the formula (II) are efficiently prepared to obtain the high allyl amine compound shown in the formula (III) under the activation of Lewis acid, and the yield can reach 85%. The method is simple, convenient and green, can efficiently obtain the target product, and has good industrial application prospect. |