| abstract |
The present invention provides a method for preparing alkylphenolic compounds from phenolic compounds and olefins. The method has the advantages of cheap and easily available raw materials, simple reaction system, simple reaction operation, wide substrate range, compatibility with CHO, COOH and other groups, excellent regioselectivity, only alkylation of phenol, and common aryl groups are not affected. Influence, no excessive alkylation products, can be used for the modification of drug intermediates and other characteristics. This method mainly solves the problems of harsh conditions such as the use of strong Lewis catalysts in other methods, poor functional group compatibility, poor selectivity, and catalyst materials need to be pre-prepared. Moreover, H 3 PO 3 plays a dual role in the same system, which can promote olefins. Generate carbocation, and can inhibit the isomerization of phenol. |