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filingDate 2019-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110974856-B
titleOfInvention Method for controlling free flavone in ginkgo leaf extract
abstract A method for controlling free flavone in a ginkgo biloba extract belongs to the technical field of natural extract purification, and comprises the following steps: (1) adjusting the pH value of feed liquid containing the ginkgo leaf extract to 5.5-7.5, and concentrating to obtain concentrated liquid; (2) clarifying the concentrated solution by flocculation, centrifugation, filtration or sedimentation to obtain clarified solution; (3) after the clarified solution is sterilized or bacteriostatic treated, macroporous adsorption resin is added, after the adsorption is finished, a resin column is washed by water-soluble alkali liquor containing ammonium ions, and then the resin column is resolved to obtain resolved solution; (4) adjusting the pH value of the resolving liquid to 5.5-7.5, concentrating and drying to obtain the ginkgo leaf extract. The invention has simple process, high ginkgo flavone yield which is more than or equal to 92 percent, and the ratio of free flavone in the ginkgo total flavone in the final product which is less than 0.5 percent, and is suitable for industrialized production.
priorityDate 2019-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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