abstract |
The pharmaceutical use of ammonium pyrrolidine dithiocarbamate, in order to improve the therapeutic effect of refractory gastritis, the present invention provides a medical use of ammonium pyrrolidine dithiocarbamate (PDTC), and it is found that PDTC is effective in the treatment of Helicobacter pylori Infection, and "omeprazole 138.2mg/kg, PDTC 28mg/kg" has a better bacteriostatic effect in mice, and the compound has better resistance and susceptibility to Helicobacter pylori in vivo and in vitro. good inhibition. |