http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110960518-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-287 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-122 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-287 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2019-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110960518-B |
| titleOfInvention | Application of the extract of goldenseal chrysanthemum in the preparation of antitumor drugs |
| abstract | The invention belongs to the technical field of medicine, and in particular relates to the application of the extract of goldenseal chrysanthemum in the preparation of antitumor drugs. The Hypericum extract is formula I: (6R, 7R, 9E)-7-hydroxy-bisabolane-2,9,11-trien-4-one and formula II: (6R, 7R, 9E)- At least one of 7-hydroxyl-11-methoxyl-bisabolane-2,9-diene-4-ketone, the compound of formula I and formula II can inhibit the proliferation of Hela human cervical cancer cells in vitro, IC 50 are 12.43μM and 25.52μM, respectively, and can be used as the main component, secondary component or additive in antitumor drugs. The invention discovers the anti-tumor activity of Rutaceae chrysanthemum, so that the plant can be used medicinally, enriches the natural medicine library resources in my country, and has obvious effects, is green and environmentally friendly, and will provide a new way and means for treating and curing tumors . |
| priorityDate | 2019-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.