http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110951719-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2402 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-14 |
| filingDate | 2019-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110951719-B |
| titleOfInvention | Biological targeted antibacterial DspB immobilized enzyme and preparation method and application thereof |
| abstract | The invention provides a preparation method of biological targeted antibacterial DspB immobilized enzyme, which is characterized in that glutaraldehyde, dopamine or succinic anhydride is used for carrying out terminal modification on a magnetic nano material, then DspB is covalently fixed on the surface of MNPs (MNPs) particles modified by terminal aldehyde groups, terminal polydopamine or terminal carboxyl through Michael addition reaction, so that the prepared biological targeted antibacterial DspB immobilized enzyme has good dispersibility, stability, magnetic responsiveness and enzyme activity, and the prepared biological targeted antibacterial DspB immobilized enzyme is easy to enrich and separate or is directionally moved and positioned due to the magnetic responsiveness, so that the DspB enzyme can form relatively high concentration in a target part under an external magnetic field, the drug effect of the biological targeted antibacterial DspB immobilized enzyme is greatly improved, and the high recycling efficiency of the biological targeted antibacterial DspB immobilized enzyme is ensured. |
| priorityDate | 2019-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.