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filingDate 2019-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110950877-B
titleOfInvention Double-detection fluorescent probe, preparation method and application thereof in detection of hydrogen sulfide and copper ions
abstract The invention provides a double-detection fluorescent probe, which has the molecular formula as follows: c 43 H 39 N 9 O 5 The preparation method of the probe comprises the following steps: dissolving the compound 2 in dry DMF, adding HOBt and EDCI at room temperature, stirring at room temperature for 30 min, adding the compound 1, stirring at room temperature overnight, after complete reaction, extracting and separating, removing the solvent to obtain a crude product, and separating by using a silica gel column to obtain the probe molecule. The probe can be applied to chemical sensing detection of hydrogen sulfide and copper ions in water environment and cells; the sensing detection comprises fluorescence detection, visual qualitative detection and cell imaging detection. The probe can be used for respectively detecting hydrogen sulfide and copper ions in cells and generating different fluorescent signals.
priorityDate 2019-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 44.