http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110946883-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6a6f422b091ba12ea61d4adbf1b0e8e |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-333 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-64 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-068 |
| filingDate | 2019-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f496242127004f77d4673857134dfb47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd885bbbb6430d6f4fb8d1214ba72582 |
| publicationDate | 2020-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110946883-A |
| titleOfInvention | A kind of preparation method of cicadae anticancer active nucleoside compound CCN1 |
| abstract | The invention discloses a preparation method of CCN1, an anticancer active nucleoside compound CCN1 of Cicada flower. The cicada flower was treated to obtain cicada pollen, and ethanol solution was added for ultrasonic treatment, followed by water bath reflux and suction filtration treatment, and the supernatant was collected by centrifugation. After adsorption treatment with macroporous adsorption resin column, the eluate of the eluted peak was collected after elution with ethanol solution, concentrated and freeze-dried; dissolved in double distilled water, centrifuged to get the supernatant, filtered through the membrane and applied to a cation exchange column, and NaCl aqueous solution was used. Gradient elution, the eluate of the water phase elution peak was collected, concentrated and freeze-dried to obtain a uniform nucleoside compound CCN1. The product prepared by the invention has uniform purity, has inhibitory effect on the growth of human gastric cancer cells, has no adverse effect on the growth of normal cells and human embryonic kidney cells, and can be used for the development of anticancer products. |
| priorityDate | 2019-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.