http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110938052-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2312575a894ab54cfff944727775f7a3
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-24
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-24
filingDate 2018-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e09b30972a6783fad924a039c5563c1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6343bd0ba90e2d2b791cb518054a3a35
publicationDate 2020-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110938052-A
titleOfInvention A kind of industrial preparation method of anti-asthma drug Prankast intermediate
abstract The invention discloses a pranlukast intermediate N-(2-cyano-4-oxo-4 H -chromene-8-yl)-4-(4-butoxyphenyl)benzamide ( Referred to as the preparation method of formula one), the method specifically refers to 4-oxo-8-[4-(4-butoxyphenyl)benzamide]-4H-chromene-2-formamide (referred to as formula two) through Dehydration reaction to prepare N-(2-cyano-4-oxo- 4H -chromene-8-yl)-4-(4-butoxyphenyl)benzamide. The preparation method of the Prankast intermediate formula 1 has the advantages of high yield, good color and high purity, which is favorable for industrial production.
priorityDate 2018-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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