http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110923309-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_217f2be73fd6be0be36dd55803d3bec5 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 |
filingDate | 2019-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6834bf1bc07e983862167181ba573da http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_526845287ee440b67cf71bcb3ba37213 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e722bb8f587a4dfc947162541aa2c8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb68bef97259d2cf00dc5758e4884bbe |
publicationDate | 2020-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110923309-A |
titleOfInvention | Biomarkers of fetal-derived adrenal insufficiency associated with dexamethasone administration during pregnancy, their primers and their applications |
abstract | The invention provides a kind of biological markers of fetal-derived adrenal insufficiency related to dexamethasone application during pregnancy, primers and applications thereof. In male or male offspring fetal-derived adrenal insufficiency associated with dexamethasone application during pregnancy, the biomarkers are peripheral blood SF-1 promoter region H3K27ac and its gene expression level, the peripheral blood The SF-1 promoter region H3K27ac and its gene expression levels can be used for early warning detection of fetal-derived adrenal insufficiency in males or male offspring associated with dexamethasone application during pregnancy. The biomarkers provided by the invention have the advantages of convenient sampling, reproducible detection, specificity, sensitivity, heritability, etc., and can be used as early warning indicators for male or male offspring fetal-derived adrenal insufficiency related to the application of dexamethasone during pregnancy , has important clinical guiding significance. |
priorityDate | 2019-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 412.