| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5bf7a0997c5ecffc9035f9619bad0c0b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-195 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6851
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N43-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N43-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N43-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y305-01018
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-025
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B15-30 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-01 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01P1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B15-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6851 |
| filingDate |
2019-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71e9f9129f3e21d9506b3f602f6d904a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7cae869d7ffa7e9608179a7ca63397a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_373e4be32d14235f937c9a9d10c2ea6a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e984945f13b5499512f6630fcbe3e96
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a27612f8ab38bf01a82ff8ea27ed1e12 |
| publicationDate |
2020-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-110923289-A |
| titleOfInvention |
A screening method for a drug for the treatment of citrus Huanglongbing |
| abstract |
The present invention provides a method for screening a drug for treating citrus huanglongbing, comprising the following steps: 1) obtaining a succinyldiaminopimelate desuccinylase gene sequence of citrus huanglongbing by comparing a database; The 5th and 15th amino acids of the succinyldiaminopimelate desuccinylase protein sequence of citrus Huanglongbing were mutated; 3) Construction of a dimer protein with two active centers; 4) Molecular docking scoring; 5 ) screening candidate compound molecules; 6) formulating a medicament for suspending water for citrus Huanglongbing diseased trees; 7) treating diseased trees; 8) taking the phloem tissue of diseased branches and extracting total DNA; 9) PCR method to select among them The candidate compound molecule with the greatest decrease in pathogen concentration is the target compound molecule. The present invention provides a screening method for a drug for treating citrus huanglongbing, and through molecular biological analysis, combined with field screening, compounds that can treat citrus huanglongbing are screened out. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111718923-A |
| priorityDate |
2019-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |