http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110917410-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-216 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-416 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-414 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-252 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-606 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-16 |
| filingDate | 2019-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110917410-B |
| titleOfInvention | Cardiovascular stent coating based on double-layer heterogeneous structure and preparation method thereof |
| abstract | The invention discloses a preparation method of a cardiovascular stent coating based on a double-layer heterogeneous structure, which comprises the following steps: 1) constructing a drug coating containing an antiproliferative drug on the cardiovascular stent; 2) mixing a double-bond end-capped polymer and a water-soluble polymer, dissolving the mixture in a solvent, spraying the mixture on a drug coating, and soaking the drug coating in water to obtain a porous coating; 3) and covering the surface of the porous coating with sulfhydrylation biomacromolecule solution containing a photoinitiator, irradiating by ultraviolet light to obtain a heparinized modified porous coating, and finally loading biological factors to obtain the cardiovascular stent coating. The invention also discloses a cardiovascular stent coating prepared by the method. The method is simple and efficient, the preparation steps are greatly simplified, and the prepared coating can enable the biological factors to be loaded with high activity, so that the compounding of the growth factors and the medicines is realized, the intimal hyperplasia can be inhibited, the rapid repair of the endothelial layer is promoted, and the better reconstruction performance of the vascular tissue is achieved. |
| priorityDate | 2019-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 89.