| abstract |
The invention belongs to the technical field of medicine, in particular to a capsule preparation containing candesartan cilexetil and a preparation method thereof. In parts by weight, 2-32 parts of candesartan cilexetil, 10-150 parts of diluent 1, 10-150 parts of diluent 2, 0.5-8 parts of disintegrant, 1-10 parts of binder, low melting point oily After mixing 0.5-10 parts of compound, pellets are prepared by extrusion spheronization method, 0.05-4 parts of lubricant is added to the pellets and mixed, and the mixture is filled into capsule shells to prepare capsule preparations. The capsule preparation containing candesartan medoxomil of the present invention adopts the preparation process of extrusion and spheronization, has high dissolution, and greatly improves the biological properties of candesartan cilexetil compared with the commercially available candesartan medoxomil preparation. Utilization. |