http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110907545-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-027 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-7266 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-34 |
| filingDate | 2019-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110907545-B |
| titleOfInvention | A method for simultaneous determination of the contents of six metabolites in Xiaojin preparations |
| abstract | The invention discloses a method for simultaneously measuring the content of six metabolites in Xiaojin preparations, wherein the six metabolites are aconitine, jungar aconitine, riolin, 3-acetyl-11-keto- β-boswellic acid, 11-keto-β-boswellic acid, and nephrine, the assay method comprises the following steps: 1) pre-processing the plasma sample to obtain a solution of the sample to be tested; 2) to the solution of the sample to be tested Positive ion internal standard and negative ion internal standard were added for HPLC‑MS/MS detection. For the first time, the present invention establishes a convenient, accurate, sensitive and reliable liquid-mass spectrometry content determination method for the six metabolites of Xiaojin preparations in vivo. The method can be applied to the serum pharmacology research of Xiaojin preparations. monitor the pharmacokinetics of drugs in vivo. |
| priorityDate | 2019-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.