http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110903233-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 |
| filingDate | 2019-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110903233-B |
| titleOfInvention | Synthetic method of a class of 3,3'-diindolylmethane derivatives |
| abstract | The present invention discloses a synthetic method of a class of 3,3′-diindolylmethane derivatives. The method uses indole and aldehydes and ketones as main raw materials, and uses sodium trifluoromethylsulfinate as a promoter, in toluene as Under the conditions of solvent, oxygen or air ambient ultraviolet light irradiation at room temperature, 3,3'-diindolylmethane derivatives can be obtained in a relatively high yield. The method has the advantages of low cost, high yield, simple operation, no pollution, etc., and has potential industrial application prospects. This method provides a cheap and green route for the preparation of 3,3'-diindolylmethane derivatives. Indole derivatives are used to inhibit bladder cancer cell biological experiments, and the results show that 3,3'-diindolylmethane derivatives have a significant and strong inhibitory effect on bladder cancer cell viability at the cellular level. |
| priorityDate | 2019-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.