http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110885831-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-998 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0606 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-545 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate | 2018-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110885831-B |
| titleOfInvention | Modified Bach1 gene and application thereof |
| abstract | The invention relates to a modified Bach1 gene and application thereof in stem cell pluripotency, self-renewal, proliferation and/or reprogramming. The activity or expression of BACH1 protein of a cell is inhibited or the activity or expression of BACH1 protein of the cell is increased by modifying a transcription factor Bach1 gene, and then the activity or expression of BACH1 protein of the cell is further interacted with de-ubiquitinated protease Usp7, pluripotency factor Nanog, Sox2 and/or Oct4, PRC2 complex, Wnt/beta-catenin signal pathway and/or Nodal/Smad2/3 signal pathway, so that the self-renewal and/or proliferation of stem cells are regulated. |
| priorityDate | 2018-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 468.