| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_117b3b5d4471ff89a53e3048a23e1513 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56911
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-14 |
| filingDate |
2019-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b282009856ebdcd10cd5e4f9bf9d541b |
| publicationDate |
2020-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-110885829-A |
| titleOfInvention |
A kind of nucleic acid aptamer DT05 of diphtheria toxin and its application |
| abstract |
The invention relates to a nucleic acid aptamer DT05 of diphtheria toxin and an application thereof. The sequence of the nucleic acid aptamer DT05 is: 5'-GTCGCATGGAAGGAGCGACGAGGGACGGTCGCGCCGTGGCGCAGGCTAGGAGAGTACGCGCGGGACCGGCGGTCCAAGT-3'. The diphtheria toxin nucleic acid aptamer DT05 of the present invention can combine with the diphtheria toxin with high affinity and high specificity, and at the same time as an antagonist, it can effectively neutralize the toxic effect of the diphtheria toxin and relieve the clinical symptoms of the diphtheria toxin poisoning. |
| priorityDate |
2019-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |