| abstract |
The invention belongs to the technical field of coating of pharmaceutical preparations, and in particular relates to a high-efficiency enteric coating composition, comprising an isolation coating layer and an enteric coating layer sequentially wrapped on the outside of a pill-containing core from the inside to the outside, wherein the isolation coating The coat includes an inner isolation layer and an outer protective layer. The formula of the inner isolation layer relative to the 185g pellet core feeding amount is 1-30g of cellulose or povidone-based water-soluble adhesive, 0.5-3g of disodium hydrogen phosphate, and purified water. 100-300g, the formula of the outer protective layer relative to the 185g pellet core feeding amount is 5-70g of cellulose-based or povidone-based water-soluble adhesive, and 10-100g of purified water. The invention can make the active substance release quickly and uniformly in the small intestine, and effectively improve the release rate of the medicine in the small intestine. |