| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b0958e008d7146f1e3bae224a6923801 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2835 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 |
| filingDate |
2019-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_070adcf791d1a2efa7f3dba2ff18f66e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_511659631a590dff8c01f122b4f61dee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f342b72788570b1988032de0bf01d60e |
| publicationDate |
2020-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-110878354-A |
| titleOfInvention |
Biomarkers for diagnosis and treatment of Parkinson's disease |
| abstract |
The invention discloses a biological marker for diagnosis and treatment of Parkinson's disease, and the biological marker is LXN. The present invention proves that LXN is differentially expressed in Parkinson's disease patients through QPCR experiment. In order to further verify the correlation between LXN and Parkinson's disease, a PD cell model is constructed to prove that interfering with LXN expression can reverse the damage effect of MPP+ on cells. LXN can be a biomarker for the diagnosis and treatment of Parkinson's disease. The research results of the present invention provide new methods and strategies for clinical diagnosis or treatment of Parkinson's disease. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111549117-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111549117-A |
| priorityDate |
2019-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |