http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110878032-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C257-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C257-14 |
| filingDate | 2019-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110878032-B |
| titleOfInvention | Synthesis method of N-benzylacetamidine hydrochloride |
| abstract | The invention discloses a method for synthesizing N-benzyl acetamidine hydrochloride, which mainly comprises three steps 1, adding benzyl hydroxylamine hydrochloride into toluene, adding sodium hydroxide aqueous solution at low temperature, and removing water layer to obtain benzyl hydroxylamine toluene solution; 2. adding acetonitrile into the hydroxylamine toluene solution, heating for reaction, and concentrating to remove the solvent after the reaction is finished to obtain an intermediate 1; 3. the intermediate 1, ethyl acetate and Raney nickel are added into an autoclave, hydrogen is introduced for hydrogenation at a certain temperature, a catalyst is filtered, a hydrogen chloride methanol solution is added, cooling and crystallization are carried out, and a target product with the purity of more than 95% is obtained. |
| priorityDate | 2019-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.