abstract |
The invention belongs to the fields of medicinal chemistry, biotechnology and medicine. The present invention provides compositions comprising one or more collagen mimetic peptides, optionally linked to one or more therapeutic compounds or one or more imaging compounds, for use in treatment, prevention, amelioration, cure and diagnosis Methods of certain diseases and physical disorders in humans and animals, and methods of making such compositions. The present invention also provides medical devices comprising one or more of such compositions of the present invention. The present invention also provides methods of using such compositions and devices for the treatment and diagnosis of certain diseases and disorders of the human and veterinary species, including ocular diseases or disorders, skin diseases or disorders, certain cancers, especially intraluminal cancers , gastrointestinal disease or disorder, genitourinary tract disease or disorder, fibrotic disease/disorder and rheumatic disease/disorder. |