http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110845595-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_67a79ebcc6c047ed9175fc6c1b23777f |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate | 2019-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52cd369b4fa8e4abfc2a3363b04e4788 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ed5db69e619a8e9d0f998fb73d2393b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bed901908be8d8165839456876062d8 |
| publicationDate | 2020-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110845595-A |
| titleOfInvention | A method for solid-phase synthesis of 5-TMARA-labeled hepcidin-25 |
| abstract | The invention relates to a method for solid-phase synthesis of 5-TMARA-labeled hepcidin-25, which belongs to the technical field of polypeptide synthesis. The steps are as follows: synthesizing the hepcidin-25 polypeptide chain; 5-TMARA labeling the polypeptide; using a DMF solution containing 2% hydrazine hydrate to remove the Dde side chain protection group on the lysine residue No. 21, and 5-TMARA fluorescent The label is attached to the lysine residue No. 21; the side chain protecting group is removed and the polypeptide is removed from the resin; the preparation of the reducing agent and the reduction of the polypeptide; purification and folding of the crude polypeptide solution; Hepcidin-25. The method of the invention adopts solid-phase synthesis, and the operation is simple, and the hepcidin-25 can be prepared in large quantities in the laboratory. The prepared hepcidin-25 has high purity, and the method has a short synthesis period. Later in vivo tracking experiments. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113817043-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113817043-B |
| priorityDate | 2019-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 76.