| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-18 |
| filingDate |
2018-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2022-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2022-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-110845574-B |
| titleOfInvention |
Polypeptide and application thereof |
| abstract |
The invention relates to a polypeptide compound Phe-Pro-Ser-Ile-Val-Gly-Arg-Pro for inhibiting dipeptidyl peptidase (DPP-IV) activity, Prolyl Endonuclease (PEP) and reducing blood sugar and resisting Alzheimer's disease, and the amino acid sequence of the polypeptide compound is Phe-Pro-Ser-Ile-Val-Gly-Arg-Pro. The polypeptide Phe-Pro-Ser-Ile-Val-Gly-Arg-Pro has DPP-IV and PEP inhibitory activity, blood sugar reducing and memory improving activity, and has good application prospect when being used as a medicine lead compound for reducing blood sugar, improving memory and resisting Alzheimer's disease. |
| priorityDate |
2018-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |