| abstract |
The present invention relates to a highly selective CSF1R inhibitor with the structure of formula (I), its preparation method and its pharmaceutical application. The compounds of the present invention can be widely used in the preparation of medicines for the treatment of cancer, tumor, autoimmune disease, metabolic disease or metastatic disease, especially for the treatment of ovarian cancer, pancreatic cancer, prostate cancer, breast cancer, cervical cancer, glioblastoma cells Cancer, multiple myeloma, metabolic diseases, neurodegenerative diseases, metastases from primary tumor sites, or drugs for bone metastases are expected to be developed into a new generation of CSF1R inhibitor drugs. |