http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110845363-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C311-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C303-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-52 |
| filingDate | 2019-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110845363-B |
| titleOfInvention | A kind of o-alkenyl aromatic nitrile compound and preparation method thereof |
| abstract | The invention belongs to the technical field of organic synthesis, and in particular relates to an o-alkenyl aromatic nitrile compound and a preparation method thereof. The present application provides an o-alkenyl aromatic nitrile compound. The structural formula of the o-alkenyl aromatic nitrile compound is shown in formula (I). The application also provides the preparation method of the o-alkenyl aromatic nitrile compound, comprising: dissolving the compound shown in the formula (II) and the compound shown in the formula (III) in an inert solvent, under alkaline conditions, the effect of an oxidizing agent and a metal catalyst The reaction is carried out to obtain the o-alkenyl aromatic nitrile compound. The method of the present application has good functional group compatibility and a wide range of substrates, and can be applied to the regioselective introduction of two functional groups, cyano and alkene, including naphthalene and indole, and can be applied to the later modification of drug molecules including probenecid Among them, it has important application potential, and effectively solves the complex technical problems of the existing conventional methods for synthesizing o-alkenyl aromatic nitrile compounds. |
| priorityDate | 2019-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 105.