http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110835634-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 |
| filingDate | 2018-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110835634-B |
| titleOfInvention | A Novel Base Conversion Editing System and Its Application |
| abstract | The present invention innovatively proposes a new type of base conversion editing system for the first time, in addition to retaining the function of a single base gene editing system—that is, to realize the conversion of a single base C/G at a designated site to T/A, and to realize the conversion of A/T to T/A. G/C conversion, and can also realize the conversion of C/G to T/A and A/T to G/C at specified sites, and the new base conversion editing system includes sgRNA, nucleic acid capable of targeting and recognizing DNA sequences Enzyme, cytosine deaminase, adenosine deaminase, uracil glucosidase inhibitor. The present invention also provides a composition or kit comprising the novel base conversion editing system, and its applications in gene editing, cytosine deaminase activity detection, adenosine deaminase activity detection, and the like. The invention breaks through the technical limitation that only a single type of base conversion can be performed in the prior art, can realize a wider range of DNA base changes, and further enrich the base editing toolbox. |
| priorityDate | 2018-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1031.