http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110835372-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-577 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2863 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-20 |
| filingDate | 2019-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110835372-B |
| titleOfInvention | Targeting Frizzled7 monoclonal antibody, and preparation method and application thereof |
| abstract | The invention relates to a targeted Frizzled7 monoclonal antibody, a preparation method and application thereof. The Frizzled 7-targeting monoclonal antibody, designated SHH002, has a heavy chain variable region comprising the following three complementarity determining regions CDRs: CDR1 shown in SEQ ID No.5, CDR2 shown in SEQ ID No.6, and CDR3 shown in SEQ ID No. 7; the light chain variable region comprises the following three complementarity determining regions CDRs: CDR1 ' shown in SEQ ID No.8, CDR2 ' shown in SEQ ID No.9, and CDR3 ' shown in SEQ ID No. 10. The invention also introduces the application of the antibody in preparing a medicament for treating tumors. The antibody of the present invention shows an ultra-high affinity for antigen (with an affinity constant of up to 1X 10) ‑12 M)。 |
| priorityDate | 2019-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 204.