http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110833537-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-258 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7092 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-489 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-258 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-489 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 |
filingDate | 2019-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110833537-B |
titleOfInvention | Drug sustained-release material and application thereof in preparing sustained-release material for treating proctitis |
abstract | The invention provides a drug sustained-release material and application thereof in a sustained-release material for treating proctitis. The outer layer of the composition is microporous hydrogel prepared from tannic acid, 3,4, 5-trihydroxybenzoic acid, deoxyadenylic acid modified gelatin, polyethylene glycol, polyvinyl alcohol and the like, the middle layer is a drug slow release layer taking poly epsilon-caprolactone and polylactic acid as chain segments, and the inner layer is condensed silica gel modified by 1H,1H,2H, 2H-perfluoroheptadecyltrimethyloxysilane and N-2- (aminoethyl) -3-aminopropyltrimethoxysilane. The drug release material combination has good adhesion performance for treating pathological organs which are not easy to be administrated, such as intracavity mucosa and the like, such as proctitis. The rectal drug sustained-release material composition has good elasticity and interface bonding strength, good biocompatibility and no toxicity or harm to human bodies. The method for improving the interface bonding force between different layers has wide application range and can be applied to a series of multilayer materials to improve the interface bonding force. |
priorityDate | 2019-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 83.