http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110806484-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b966910e0c48a1f1938186fb9b616644 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57434 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
| filingDate | 2019-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eaa096ffab9e2a4e2c5af473673e800e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bed083bba93ac1fcf33341c5f62e5807 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5c3fad617fed191fd45224dfc0ff540 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bacca9904b11aacdcf8a49d24ab28152 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8ac4d76ba94053595a7a54f12e4f8c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e9af7380506dda8fdc683ae54d3ef8b |
| publicationDate | 2020-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110806484-A |
| titleOfInvention | A sarcosine detection method based on single-walled carbon nanotubes and nucleic acid aptamers |
| abstract | The invention relates to a detection method for the determination of sarcosine, a specific target of prostate cancer, in particular to a method for adsorbing fluorescent carbon nanotubes based on nucleic acid aptamers to form a monodisperse solution; then the nucleic acid aptamers recognize sarcosine, and the surface of the carbon nanotubes is detected by the nucleic acid aptamers. Dissociation, aggregation of carbon nanotubes, quenching of fluorescence, and determination of sarcosine content. The advantages of the present invention are: (1) The detection system constructed by the present invention does not require functional modification of SWNTs, nor any labeling of ss-DNA, and is a label-free detection method with fast and simple detection. (2) The present invention uses the near-infrared fluorescence of monodisperse SWNTs for detection, which avoids the error caused by the autofluorescence of biological tissue and body fluid samples, and is beneficial to be directly applied to the detection of sarcosine content in blood or urine. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112858432-A |
| priorityDate | 2019-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.