| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_653c418e41edbb4e1ce8bc5e53e70cec |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-84 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0697
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2019-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02f5d0f765b9b8c38bdb30b73d794c06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_300f911470d8ae5e8a829507f376bd3e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f19f635466c4db39b218182c004ff47d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5f0c7402128675a5720377d9eb1909f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db79356838a11023ac3f60e481fe5449
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f4e3309f8dfbe61bafedfb71ba98a57 |
| publicationDate |
2020-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-110804580-A |
| titleOfInvention |
A kind of culture method for forming early micro hair follicle in vitro and its application |
| abstract |
The invention provides a culture method for forming early micro-hair follicles in vitro and its application. The culturing method includes: mixing dermal progenitor cells and epidermal stem cells, suspending culture in a medium to form dermal-epidermal aggregates, and collecting the cultured hair follicle-like structures to be cultured hair follicle-like micro-organs. This method enables the formation of a large number of hair follicle micro-organ structures (aggregates) within 24 hours only by a simple suspension method using scalp dermal progenitor cells and foreskin epidermal stem cells. At the same time, the in vivo transplantation experiments further confirmed that the in vitro cultured hair follicle micro-organs can form mature hair follicles in vivo. The present invention lays a good foundation for studying hair follicle epithelium-interstitial interaction, evaluating induced hair stem cells, screening those supporting hair follicle regeneration, and applying to clinical treatment of hair loss in the future. |
| priorityDate |
2019-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |