http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110804079-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 |
| filingDate | 2019-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110804079-B |
| titleOfInvention | Furocoumarin with DPPIV enzyme inhibitory activity and preparation method thereof |
| abstract | The invention provides furocoumarin with DPPIV enzyme inhibitory activity and a preparation method thereof. The furocoumarin compound 6-beta-D-glucosyl-6, 7-dihydroxy-5-benzofuran methyl propionate has the structural formula shown in formula (I), and is obtained by separating dried or fresh fruits, roots, stems, branches or leaves of clausena lansium. In vitro pharmacological experiments prove that the compound 6-beta-D-glucosyl-6, 7-dihydroxy-5-benzofuranmethyl propionate has obvious inhibition effect on DPPIV enzyme, and IC of the compound 50 The value was 117. + -. 8.7. mu.M, indicating good DPPIV enzyme inhibitory activity. The furocoumarin compound 6-beta-D-glucosyl-6, 7-dihydroxy-5-benzofuranmethyl propionate is expected to be used as a lead compound to develop a novel DPPIV enzyme inhibitor drug. |
| priorityDate | 2019-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 157.