http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110790775-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-36 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-36 |
filingDate | 2019-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110790775-B |
titleOfInvention | Preparation method of cefazolin sodium impurity B |
abstract | The invention discloses a preparation method of cefazolin sodium impurity B. The invention takes cefazolin mother nucleus as raw material, and obtains cefazolin sodium impurity B by acylation reaction with pivaloyl chloride, crystallization, pulping, filtration and drying. The method has mild reaction conditions, does not relate to ultralow temperature reaction, reduces process steps, and is suitable for pilot scale of laboratories. The cefazolin sodium impurity B prepared by the method has high yield, the purity reaches 95 percent, the requirement of the research on the quality of the cefazolin sodium can be met, and a technical basis is provided for the improvement of the national quality standard of the cefazolin sodium. |
priorityDate | 2019-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.