| abstract |
The invention provides a ligustrazine film coating agent and a preparation method thereof, belonging to the technical field of film coating agent preparation. The ligustrazine film coating agent comprises the following components by weight: 3-20 parts of ligustrazine, 3 ～15 parts, plasticizer 2～10 parts, organic solvent 5～25 parts, surfactant 0.1～1 part, penetration enhancer 0.3～1.3 parts, water 27.7～86.6 parts. The ligustrazine film coating agent provided by the invention has the advantages of quick effect, long-lasting action, good spreadability, strong adhesion, no irritation to the skin, and convenient administration; It has the characteristics of high safety, good compliance and large sample load, and can continuously and stably release the drug within a specified time, and the blood drug concentration is stable, which fundamentally eliminates the defects of ligustrazine injection and tablet. |