http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110776460-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1029 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1007 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-64 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
filingDate | 2019-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110776460-B |
titleOfInvention | Fluorescent compound for LED visible light induced release of nitric oxide and preparation and application thereof |
abstract | The invention relates to a LED, a fluorescent compound (I) capable of releasing nitric oxide under the induction of visible light, and a preparation method and application thereof. The compound (I) can sufficiently release nitric oxide under the induction of LED yellow light, and reaches the concentration of the nitric oxide released by similar compounds under the induction of ultraviolet; meanwhile, the fluorescence response induced by LED yellow light (18W) in the PBS solution is higher than that induced by common ultraviolet light (8W), so that the method is better applied to cell biological imaging; according to the invention, the LED yellow light source is used as a trigger light source for nitric oxide release, and the two-photon dye is used as a compound fluorescent parent, so that the phototoxicity is greatly reduced during application, and the damage to organisms and cells is reduced; due to the good light stability and thermal stability of the conjugated structure containing the naphthalimide, the compound (I) can be irradiated in organisms for a long time and can continuously release nitric oxide for a long time, and can be applied to inhibiting the proliferation of cancer cells. |
priorityDate | 2019-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.