http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110776409-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-481 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C46-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C50-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C46-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2019-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110776409-B |
| titleOfInvention | A kind of extraction method of Indian Dalbergia and application of the extract in antitumor drugs |
| abstract | The invention relates to a method for extracting Indian Dalbergia, which is Leguminosae Dalbergia Dalbergia plant Dalbergia sissoo Roxb.; the extract comprises alcohol extract, ether extract and petroleum ether extract; The isolated monomer is 4-Methoxydalbergione. Specifically comprising the following steps: taking the heartwood of Indian Dalbergia, slicing it into thin slices, pulverizing and passing through a No. 2 sieve, the extraction solvent is ethanol or methanol solution, the material-to-liquid ratio is 1:2-1:8, heating and refluxing extraction 2-5 times, 1‑3h each time. Filter while hot, combine the filtrates, and concentrate under reduced pressure to form a dilute extract. It has been confirmed by cell experiments that Dalbergia indica has important medicinal value. Its monomer can significantly inhibit the proliferation of human hepatoma cells HepG2, human breast cancer cells MCF-7, mouse breast cancer cells 4T1 and human glioma cells U87, and affect their morphological functions. It will provide a basis for the development and utilization of Indian Dalbergia, and provide new options for the research and development of anti-tumor drugs. |
| priorityDate | 2019-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.