http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110770220-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-454 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 |
| filingDate | 2018-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110770220-B |
| titleOfInvention | Preparation and purification method of eficonazole |
| abstract | Provided is a method for preparing and purifying eficonazole, which can provide high-purity eficonazole with a high yield and is suitable for industrial scale by taking specific impurities as an index and simple operation. The present production method is characterized by including the following steps. That is, step A: a step of forming a toluene solution containing compound (II), compound (III), an inorganic base, and 2 to 5 times the volume (L) of compound (II) mass (Kg) Toluene; Step B: the step of carrying out heating reaction to the toluene solution; Step C: the step of obtaining the toluene solution of the crude product of eficonazole, i.e. the reaction solution of washing step B, thus the residual amount of 4-MP is relative to the Ficonazole is below 5wt%. |
| priorityDate | 2017-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.