http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110763799-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-8822 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-88 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88 |
| filingDate | 2019-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110763799-B |
| titleOfInvention | Method for simultaneously detecting quetiapine and N-dealkylated quetiapine contents in blood |
| abstract | The invention provides a method for simultaneously detecting the content of quetiapine and N-dealkylated quetiapine in blood. Preparing at least three standard working solutions containing quetiapine standard substances with known concentration and N-dealkylated quetiapine standard substances; mixing the standard working solution, the internal standard working solution and the blank blood sample, and performing sample pretreatment to obtain a standard solution; respectively detecting each standard solution by using a high performance liquid chromatograph to obtain a chromatogram of each standard solution; fitting to obtain a standard curve equation according to the chromatogram of each standard solution; mixing the internal standard working solution with a blood sample obtained by treating blood to be detected, and performing the same sample pretreatment to obtain a sample to be detected; detecting the sample to be detected to obtain a chromatogram map; and calculating the contents of the quetiapine and the N-dealkylated quetiapine in the blood sample according to the chromatogram of the sample to be detected and each standard curve equation. The invention can simultaneously detect the contents of quetiapine and N-dealkylated quetiapine in blood. |
| priorityDate | 2019-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.