| abstract |
The present invention relates to a class of genipin derivatives containing ester, oxime and hydrazone fragments, their preparation method and their application as pesticides. The general formulas (I-a and I-b) of the present invention show excellent insecticidal activity against the adult mites of Tetranychus cinnabarinus, and the genipin acyl hydrazone I-b-5 even reaches 80% at a concentration of 200 mg/L, which can effectively prevent and control cinnabar. The damage of spider mites to a variety of crops. In addition, the general formulas (I-a and I-b) of the present invention have excellent insecticidal activity against lepidopteran pests, wherein the insecticidal LC 50 value of compound I-a-14 to diamondback moth is 40.4 mg/L (95 % confidence interval was 23.5-69.7mg/L), showing excellent activity against diamondback moth. The general formulas (I-a and I-b) of the present invention have excellent bacteriostatic activity against 14 common phytopathogenic bacteria, and can effectively prevent and treat fungal diseases of various crops. The specific compound structures, synthesis steps and biological activities are detailed in the instructions. |