http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110755379-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2019-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110755379-B |
| titleOfInvention | Targeted drug delivery system capable of resisting drug-resistant tumors and preparation method thereof |
| abstract | The invention discloses a targeted drug delivery system capable of resisting drug-resistant tumors and a preparation method thereof. Experiments prove that: the targeted drug delivery system has certain acid sensitivity, can be actively released under the condition of a tumor microenvironment, can be quickly diluted by blood after entering the blood, cannot cause serious hemolysis, has higher safety, is suitable for intravenous injection administration, can reverse the drug resistance of drug-resistant tumor cells to a certain degree, can obviously improve the sensitivity of the drug-resistant tumor cells to chemotherapeutic drugs, can increase the accumulation of the chemotherapeutic drugs at tumor parts, obviously improves the treatment effect of the chemotherapeutic drugs on drug-resistant tumors, has good tumor targeting effect and has no obvious toxic or side effect; in addition, the preparation method is easy to realize, simple to operate and good in repeatability. |
| priorityDate | 2019-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.