http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110746476-A

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filingDate 2019-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93404a4fd650f84bf478bb62476912a9
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publicationDate 2020-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110746476-A
titleOfInvention A kind of 5-azacytosine nucleoside compound and preparation method thereof
abstract The present invention relates to a 5-azacytosine nucleoside compound and a preparation method thereof, whose structural formula is shown in formula I. The compound is obtained by using 5-azacytosine as a starting material and through the reaction steps of upper protection, condensation, deprotection, re-condensation and deprotection. Through the research on this related substance, the understanding and control of the impurity spectrum in 5-azacytosine nucleoside compounds have been strengthened; it is beneficial to the quality control of finished products and provides a guarantee for the safety of clinical medication. The synthesis process is simple to operate, has good yield and purity, and is environmentally friendly.
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