| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_785aef5376e92b3280401f44b8f6233d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-181 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-80 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 |
| filingDate |
2019-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fa772fb529526f01238419d421cf510
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a182921b46fc253704b37b3a9451ec05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4a7f199531a8efa3fad1cd9bed6efae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_135d3fb4aca26e68868f1160f129ca8f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fee2a1f14b2007f8cc4599455b482b2b |
| publicationDate |
2020-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-110746446-A |
| titleOfInvention |
Dimeric tetrahydro xanthene compound and preparation method and application thereof |
| abstract |
The invention discloses a dimeric tetrahydro Xanthone compound and a preparation method and application thereof. The structure of the dimeric tetrahydro xanthene compound is shown as the formula (I). The invention separates four new dimeric tetrahydro xanthene compounds from a Penicillium purpurogenum SC0070 fermentation product, and bacteriostatic tests show that the compounds can treat staphylococcus aureus (MSSA)) The compounds have obvious inhibition effect on methicillin-resistant staphylococcus aureus (MRSA) and Shigella dysenteriae (Shigella dysenteria), in-vitro anti-tumor tests show that the compounds have obvious cytotoxic activity on tumor cell strains, namely human lung cancer cells A549, human cervical cancer cells Hela and human hepatoma cells HepG, and have selectivity on normal cells Vero of African green monkey kidney cells, and the compounds can be used as antibacterial agents, cell proliferation inhibitors or antitumor drugs in medicines. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112300243-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112300243-A |
| priorityDate |
2019-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |