http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110746339-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1029 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6417 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-34 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-34 |
filingDate | 2019-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110746339-B |
titleOfInvention | A kind of pyrrole bihydrazone derivative fluorescent probe and its preparation method and application |
abstract | The present invention provides a pyrrole bishydrazone derivative fluorescent probe and a preparation method and application thereof, wherein the chemical structural formula of the pyrrole bishydrazone derivative is as follows: The preparation method is: N-morpholinoethyl-2,4-dimethyl-5-formylpyrrole-3-formamide and hydrazine hydrate are dissolved in an organic solvent; The reaction was refluxed and stirred for 3-4 h at 80°C; the obtained solution was cooled to room temperature, filtered under reduced pressure, and the obtained solid residue was washed with ethanol to obtain the pyrrole bishydrazone derivative fluorescent probe. The fluorescent probe of the pyrrole dihydrazone derivative of the present invention can selectively interact with mercury ions under physiological conditions, the solution changes from colorless to green, and the blue fluorescence is significantly enhanced, especially as a fluorescent probe in cell lysosomes Applications for convenient detection of mercury ions. |
priorityDate | 2019-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.