http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110724180-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 |
| filingDate | 2019-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110724180-B |
| titleOfInvention | A kind of polypeptide that inhibits angiogenesis and its application |
| abstract | The invention provides a polypeptide for inhibiting angiogenesis and its application. The invention systematically studies the activity of Tat itself and further designs and synthesizes new polypeptide chains transTat, RGDGtransTat and transTatGRGD on the basis of Tat. Among them, RGDGtransTat and transTatGRGD showed better inhibition of angiogenesis (including inhibition of HUVEC proliferation, migration and tubulogenesis), and showed a certain dose-effect relationship. The polypeptide of the present invention can not only be used to prevent or treat diseases related to angiogenesis by inhibiting angiogenesis, but also can be used as an angiogenesis inhibitor to inhibit the angiogenesis of endothelial cells in vitro, thereby providing materials for scientific research related to angiogenesis. It has good prospects for practical application. |
| priorityDate | 2019-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.