http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110724087-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1029 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0057 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
filingDate | 2019-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110724087-B |
titleOfInvention | Organic long-afterglow compound and preparation method and application thereof |
abstract | The invention discloses an organic long afterglow type compound and a preparation method and application thereof, belonging to the technical field of photodynamic therapy. The invention designs and synthesizes an organic long afterglow class compound with a brand new structure based on oxygen group elements, and has the following advantages: 1. the imaging time is long, and is improved from nanosecond imaging of the traditional fluorescence imaging agent to millisecond imaging of the organic long afterglow material; 2. introducing oxygen group elements into the organic long afterglow compounds improves the yield of the triplet excitons of molecules and promotes the generation of active oxygen; 3. the excitation can be extended to visible light, so that a better treatment effect can be easily achieved under the irradiation of the visible light, and the biological toxicity is low; 4. has good biocompatibility. Experiments prove that the compound has obvious inhibitory activity on gram-positive bacteria, so the compound has the potential of being used as a photosensitizer for effective photodynamic therapy. |
priorityDate | 2019-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.